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Diederick E Grobbee Selected Research

aleglitazar

1/2020Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial.
1/2018Adiponectin, Free Fatty Acids, and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Acute Coronary Syndrome.
1/2018Homeostasis Model Assessment of Insulin Resistance and Survival in Patients With Diabetes and Acute Coronary Syndrome.
1/2018Predictors of mortality in hospital survivors with type 2 diabetes mellitus and acute coronary syndromes.
1/2017The haemoglobin glycation index as predictor of diabetes-related complications in the AleCardio trial.
1/2017Post-Discharge Worsening Renal Function in Patients with Type 2 Diabetes and Recent Acute Coronary Syndrome.
4/2014Effect of aleglitazar on cardiovascular outcomes after acute coronary syndrome in patients with type 2 diabetes mellitus: the AleCardio randomized clinical trial.
9/2013Evaluation of the dual peroxisome proliferator-activated receptor α/γ agonist aleglitazar to reduce cardiovascular events in patients with acute coronary syndrome and type 2 diabetes mellitus: rationale and design of the AleCardio trial.

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Diederick E Grobbee Research Topics

Disease

57Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 04/2002
37Type 2 Diabetes Mellitus (MODY)
01/2021 - 04/2002
29Hypertension (High Blood Pressure)
12/2020 - 11/2002
23Atherosclerosis
01/2021 - 08/2002
23Breast Neoplasms (Breast Cancer)
01/2018 - 07/2003
19Coronary Disease (Coronary Heart Disease)
11/2020 - 01/2003
19Heart Failure
10/2020 - 02/2002
18Myocardial Infarction
01/2021 - 07/2002
16Vascular Diseases (Vascular Disease)
01/2018 - 08/2003
15Stroke (Strokes)
01/2021 - 08/2005
12Insulin Resistance
12/2018 - 08/2002
11Pneumonia (Pneumonitis)
10/2019 - 05/2014
11Inflammation (Inflammations)
01/2019 - 03/2004
10Diabetes Mellitus
01/2022 - 11/2002
10Acute Coronary Syndrome
01/2020 - 07/2002
10Neoplasms (Cancer)
11/2013 - 02/2004
10Coronary Artery Disease (Coronary Atherosclerosis)
08/2013 - 05/2002
9Infections
01/2022 - 03/2015
8HIV Infections (HIV Infection)
12/2020 - 11/2015
8Obesity
11/2018 - 04/2006
7Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2013 - 05/2005
6Chronic Disease (Chronic Diseases)
12/2020 - 06/2002
6Overweight
01/2017 - 09/2004
6Schizophrenia (Dementia Praecox)
06/2011 - 04/2006
5Pneumococcal Infections
10/2019 - 03/2015
5Congenital Heart Defects (Congenital Heart Defect)
01/2017 - 07/2008
5Pre-Eclampsia (Preeclampsia)
09/2015 - 09/2008
5Cognitive Dysfunction
10/2013 - 03/2002
5Chronic Obstructive Pulmonary Disease (COPD)
01/2013 - 09/2005
5Body Weight (Weight, Body)
06/2010 - 05/2004
4COVID-19
01/2022 - 06/2021
4Diabetes Complications
10/2021 - 01/2017
4Atherosclerotic Plaque (Atheroma)
11/2020 - 01/2003
4Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced)
03/2018 - 09/2015
4Birth Weight (Birth Weights)
01/2017 - 01/2006
4Heart Diseases (Heart Disease)
01/2014 - 02/2005
4Psychotic Disorders (Schizoaffective Disorder)
02/2011 - 04/2006
4Carotid Artery Diseases
07/2007 - 12/2003
3Genetic Risk Score
10/2021 - 01/2017
3Myocardial Ischemia (Ischemic Heart Diseases)
07/2020 - 09/2009

Drug/Important Bio-Agent (IBA)

25Glucose (Dextrose)FDA LinkGeneric
10/2021 - 08/2002
16Biomarkers (Surrogate Marker)IBA
01/2022 - 05/2007
15LipidsIBA
01/2021 - 01/2003
13Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2021 - 01/2003
13HDL CholesterolIBA
12/2020 - 02/2004
13CholesterolIBA
11/2018 - 04/2004
12VaccinesIBA
10/2021 - 02/2005
12Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2019 - 07/2002
12Insulin (Novolin)FDA Link
01/2018 - 10/2002
10Hormones (Hormone)IBA
12/2011 - 03/2004
9Pharmaceutical PreparationsIBA
10/2021 - 11/2006
9Gliclazide (Diamicron)IBA
01/2018 - 08/2003
9Estrogens (Estrogen)FDA Link
08/2009 - 11/2003
8Proteins (Proteins, Gene)FDA Link
10/2020 - 11/2004
8aleglitazarIBA
01/2020 - 09/2013
8perindopril drug combination indapamideIBA
01/2018 - 08/2003
8LDL CholesterolIBA
01/2017 - 10/2002
8Testosterone (Sustanon)FDA Link
02/2011 - 11/2003
8Gonadal Steroid Hormones (Sex Hormones)IBA
01/2009 - 08/2003
7Triglycerides (Triacylglycerol)IBA
12/2020 - 11/2002
7Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2020 - 01/2008
7Conjugate VaccinesIBA
01/2019 - 03/2015
7Rosuvastatin Calcium (Crestor)FDA Link
11/2018 - 05/2004
7PerindoprilFDA LinkGeneric
01/2015 - 05/2002
7Antipsychotic Agents (Antipsychotics)IBA
06/2011 - 05/2004
6Blood Glucose (Blood Sugar)IBA
01/2022 - 12/2002
6oxidized low density lipoproteinIBA
01/2021 - 09/2004
6CoffeeFDA Link
12/2020 - 05/2005
6Bisoprolol (Concor)FDA LinkGeneric
01/2017 - 07/2008
6Phytoestrogens (Phytoestrogen)IBA
02/2005 - 06/2002
5CreatinineIBA
11/2020 - 02/2007
5Brain Natriuretic Peptide (Natrecor)FDA Link
01/2017 - 06/2007
5CalciumIBA
10/2016 - 12/2006
5Anti-Bacterial Agents (Antibiotics)IBA
11/2015 - 12/2002
5IndapamideFDA LinkGeneric
01/2015 - 01/2007
5Estradiol (Delestrogen)FDA LinkGeneric
01/2009 - 05/2004
5AndrogensIBA
10/2006 - 08/2003
4AntibodiesIBA
10/2021 - 01/2019
4Indicators and Reagents (Reagents)IBA
01/2021 - 12/2002
4EnzymesIBA
01/2020 - 04/2005
4Antihypertensive Agents (Antihypertensives)IBA
01/2019 - 03/2004
4pro-brain natriuretic peptide (1-76)IBA
01/2018 - 12/2005
4Hydrochlorothiazide (Esidrix)FDA LinkGeneric
01/2017 - 01/2011
4Lisinopril (Prinivil)FDA LinkGeneric
01/2017 - 01/2011
4Simvastatin (Zocor)FDA LinkGeneric
01/2017 - 01/2011
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
10/2014 - 05/2002
4DiureticsIBA
05/2011 - 10/2003
4Insulin-Like Growth Factor I (IGF-1)IBA
11/2008 - 08/2003
4SteroidsIBA
01/2007 - 03/2005
4IronIBA
04/2006 - 02/2005
3AntigensIBA
10/2021 - 03/2015
3HDL LipoproteinsIBA
10/2020 - 04/2007

Therapy/Procedure

42Therapeutics
01/2021 - 04/2002
8Secondary Prevention
01/2020 - 05/2009
4Wearable Electronic Devices
01/2022 - 06/2021
4Art Therapy
12/2020 - 12/2016
4Hormone Replacement Therapy (Therapy, Hormone Replacement)
06/2008 - 03/2004
4Cardiopulmonary Bypass (Heart-Lung Bypass)
09/2007 - 03/2002
4Caloric Restriction
02/2007 - 02/2004
3Radiotherapy
01/2021 - 01/2016